PUBLICATIONS2018-09-03T17:03:00+00:00

2018

Zhu X, Li S, Pan S, Xin X, Gu Y (2018) CSI1, PATROL1 and exocyst complex cooperate in delivery of cellulose synthase complexes to the plasma membrane. Proc. Natl. Acad. Sci. USA 115:E3578-3587. Link

2016

Li S, Bashline L, Zheng Y, Xin X, Huang S, Kong Z, Kim SH, Cosgrove D, Gu Y (2016) Cellulose synthase complexes act in a concerted fashion to synthesize highly aggregated cellulose in secondary cell walls of plants. Proc. Natl. Acad. Sci. USA 113(40): 11348-11353  Link

Wang C, Hu T, Yan X, Meng T, Wang Y, Wang Q, Zhang X, Gu Y, Sánchez-Rodríguez C, Gadeyne A, Lin J, Persson S, Van Damme D, Li C, Bednarek SY, Pan J (2016) Differential regulation of Clathrin and its adaptor proteins during their membrane recruitment in Arabidopsis. Plant Physiol. 171(1): 215-229  Link

2015

Lei L, Singh A, Bashline L, Li S, Yingling YG, Gu Y (2015) The Arabidopsis cellulose synthase interactive 1 is required for a fast recycling of cellulose synthase complex to the plasma membrane. Plant Cell 27(10): 2926-2940  Link

Bashline L, Li S, Zhu X, Gu Y (2015) The TWD40-2 protein and the AP2 complex cooperate in the clathrin-mediated endocytosis of cellulose synthase to regulate cellulose biosynthesis. Proc. Natl. Acad. Sci. USA 112(41):12870-12875  Link

Wang S, Chen XA, Hu J, Jiang JK, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y (2015) ATF4 gene network mediate cellular response to the anticancer PAD4 inhibitor YW3-56. Mol. Cancer Ther. 14:877-888. PMID: 25612620  Link

2014

Brabham C, Lei L, Stork J, Barrett M, Gu Y, Debolt S (2014) Indaziflam herbicidal action: a potent cellulose biosynthesis inhibitor. Plant Physiol. 166(3):1177–1185  Link

Lei L, Zhang T, Strasser R, Lee CM, Gonneau M, Mach L, Vernhettes S, Kim SH, Cosgrove D, Li S, Gu Y (2014) The jiaoyao1 mutant is an allele of korrigan that affects the organization of both cellulose microfibrils and microtubules in Arabidopsis. Plant Cell 26(6):2601-2616  Link

Ye X, Lei L, Stork J, Brabham C, Strickland J, Ladak A, Gu Y, Debolt S (2014) Microbial natural product-based bioprospecting: identification of acetobixan as an inhibitor of plant cellulose biosynthesis. PLoS ONE DOI: 10.1371/journal.pone.0095245  Link

2013

Lei L, Li S, Du J, Gu Y (2013) Cellulose synthase interactive 3 regulates cellulose biosynthesis in both microtubule-dependent and microtubule-independent manner. Plant Cell 25(12):4912-4923  Link

Bashline L, Li S, Anderson CT, Lei L, Gu Y (2013) The endocytosis of cellulose synthase in Arabidopsis is dependent on u2, a clathrin mediated endocytosis adaptin. Plant Physiol. 163(1):150-160  Link

Chang F, Gu Y, Ma H, Yang Z (2013) AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth. Mol. Plant 6(4):1187-1201  Link

Li S, Lei L, Gu Y (2013) Functional analysis of complexes with mixed primary and secondary cellulose synthases. Plant Signal. Behav. 8(3): e23179  Link

2012

Carroll A, Mansoori N, Li S, Lei L, Vernhettes S, Visser R, Somerville C, Gu Y, Trindade, L (2012) Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants. Plant Physiol. 160(2):726-737   Link

Wang Y, Li P, Wang S, Hu J, Chen XA, Wu J, Fisher M, Oshaben K, Zhao N, Gu Y, Chen G, Wang Y. (2012) Anticancer PAD inhibitors regulate autophagy and the mammalian target of rapamycin complex 1 activity. J. Biochem. Chem. 287(31):25941-25953  Link

Lei L, Li S, Gu Y (2012) Cellulose synthase interactive protein 1 (CSI1) mediates the intimate relationship between cellulose microfibrils and cortical microtubules. Plant Signal. Behav. 7(7):714-718  Link

Li S, Lei L, Somerville CR, Gu Y (2012) Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc. Natl. Acad. Sci. USA 109(1):185-190  Link

2010

Gu Y, Kaplinsky N, Bringmann M, Cobb A, Carroll A, Sampathkumar A, Baskin TI, Persson S, Somerville C (2010) Identification of a cellulose synthase-associated protein required for cellulose biosynthesis. Proc. Natl. Acad. Sci. USA 107:12866-12871  Link

Publications before joining Penn State:

Gu Y, Deng ZP, Paredez AR, Debolt S, Wang ZY, Somerville C (2008) Prefoldin6 is required for normal microtubule dynamics and organization in Arabidopsis. Proc. Natl. Acad. Sci. USA 105:18064-18069  Link

Li S, Gu Y, Yan A, Lord E, Yang ZB (2008) RIP1 (ROP Interactive Partner 1)/ICR1 marks pollen germination sites and may act in the ROP1 pathway in the control of polarized pollen growth. Mol. Plant 6:1021-1035  Link

Jeon BW, Hwang JU, Hwang YK, Song WY, Fu Y, Gu Y, Bao F, Cho D, Kwak JM, Yang ZB, Lee Y (2008) The Arabidopsis small G protein ROP2 is activated by light in guard cells and inhibits light-induced stomatal opening. Plant Cell 20:75-87  Link

Gu Y, Li SD, Lord EM, Yang ZB (2006) Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Plant Cell 18:366-381  Link

Fu Y, Gu Y, Zheng ZL, Wasteneys G, Yang ZB (2005) Arabidopsis interdigitating cell growth requires two antagonistic pathways with opposing action on cell morphogenesis. Cell 120:687-700  Link

Gu Y, Fu Y, Dowd P, Li SD, Vernoud V, Gilroy S, Yang ZB (2005) A Rho-family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. J. Cell Biol. 169:127-138  Link

Hwang JU, Gu Y, Lee YJ, Yang ZB (2005) A Oscillatory ROP GTPase activation leads the oscillatory polarized growth of pollen tubes. Mol. Biol. Cell 16:5385-5399  Link

Park J, Gu Y, Lee Y, Yang ZB, Lee Y (2004) Phosphatidic acid induces leaf cell death in Arabidopsis by activating the Rho-related small G protein GTPase-mediated pathway of reactive oxygen species generation. Plant Physiol. 134:129-136  Link

Gu Y, Vernoud V, Fu Y, Yang ZB (2003) ROP GTPase regulation of pollen tube growth through the dynamics of tip-localized F-actin. J Exp. Bot. 54:93-101  Link

Wu G, Gu Y, Li SD, Yang ZB (2001) A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-containing proteins that act as Rop GTPase targets. Plant Cell 13:2841-2856  Link

2015

Li S, Lei L, Yingling YG, Gu Y (2015) Microtubules and cellulose biosynthesis: the emergence of new players. Curr. Opin. Plant Biol. 28: 76-82  Link

2014

Lei L, Li S, Bashline L, Gu Y (2014) Dissecting the molecular mechanism underlying intimate relationship between cellulose microfibrils and cortical microtubules. Front. Plant Sci. doi: 10.3389/fpls.2014.00090  Link

Bashline L, Li S, Gu Y (2014) Trafficking of the cellulose synthase complex in higher plants. Ann. Bot. doi: 10.1093/aob/mcu040  Link

Bashline L, Lei L, Li S, Gu Y (2014) Cell wall, cytoskeleton, and cell expansion in higher plants.  Mol. Plant 7(4): 586-600  Link

Li S, Bashline L, Lei L, Gu Y (2014) Cellulose biosynthesis and its regulation. The Arabidopsis Book 11:e0169. doi:10.1199/tab.0169  Link

2012

Li S, Gu Y (2012) Cellulose biosynthesis in higher plants and the role of the cytoskeleton. eLS doi: 10.1002/9780470015902.a0023745  Link

Baskin T, Gu Y (2012) Making parallel lines meet: Transferring information from microtubules to extra-cellular matrix. Cell Adhe. Migr. 6(5):1-5  Link

Lei L, Li S, Gu Y (2012) Cellulose synthase complexes: composition and regulation. Front. Plant Physiol. 3:75 doi: 10.3389/fpls.2012.00075  Link

2011

Bashline L, Du J, Gu Y (2011) The trafficking and behavior of cellulose synthase and a glimpse of potential cellulose synthesis regulators. Front. Biol. 6(5):377-383  Link

2010

Gu Y, Somerville C (2010) Cellulose synthase interacting protein: a new factor in cellulose synthesis. Plant Signal. Behav. 5(12):1571-1574  Link

Publications before joining Penn State:

Gu Y, Wang ZH, Yang ZB (2004) ROP/RAC GTPase: an old new master regulator for plant signaling. Curr. Opin. Plant Biol. 7:527-536  Link

Bashline L, Gu Y (2015) Using the Split-Ubiquitin yeast two-hybrid systems to test protein-protein interactions of transmembrane proteins. In: Plant Cell Expansion: Methods and Protocols. Method. Mol. Biol. vol. 1242, DOI 10.1007/978-1-4939-1902-4_13, Springer Science, New York.  Link

Xiaoyu Zhu received the 2018 Robert T. Simpson Graduate Student Award for Innovative Research. Link

Penn State News highlighted the research from Gu Lab: “New insights into how cellulose is built could indicate how to break it apart for biofuels.” Link

A Penn State Research article highlights the research of Gu LAB researchers at Penn State: “The key to efficient biofuels may lie in learning how plants build their cell wall.” Full story (page 21-24): Link

Logan Bashline was invited to make a video of his current work to be used as part of a video series that showcases the accomplishments of successful Waynesburg alumni.