2024
Allen H, Zhu X, Li S, Gu Y (2024) The TRAPPIII subunit, Trs85, has a dual role in the trafficking of cellulose synthase complexes in Arabidopsis. Plant Journal, doi: 10.1111/tpj.16688. Link
Allen H, Davis B, Patel J, Gu Y (2024) Dot Scanner: Open-source software for quantitative live-cell imaging in planta. Plant Journal, doi: 10.1111/tpj.16662. Link
Rongpipi S, Barnes WJ, Siemianowski O, Ye D, Del Mundo JT, Duncombe S, Xin X, Zhu C, Toney MF, Gu Y, Anderson CT, Gomez ED, Gomez EW (2024) Matrix Polysaccharides affect preferred orientation of cellulose crystals in primary cell walls. Cellulose, 31, 1397-1415. Link
2023
Lee J, Choi J, Feng L, Yu J, Zheng Y, Zhang Q, Lin YT, Sah S, Gu Y, Zhang S, Cosgrove DJ, Kim SH (2023) Regiospecific cellulose orientation and anisotropic mechanical property in plant cell walls. Biomacromolecules, 24, 4759-4770. Link
Murshed M, Wei D, Gu Y, Wang J (2023) Simulation of microtubule-cytoplasm interaction revealed the importance of fluid dynamics in determining the organization of microtubules. Plant Direct 7, e505. Link
Xin X, Wei D, Lei L, Zheng H, Wallace I, Li S, Gu Y (2023) CALCIUM-DEPENDENT PROTEIN KINASE32 regulates cellulose biosynthesis through post-translational modification of cellulose synthase. New Phytologist Link
Xin X, Wei D, Lei L, Zheng H, Wallace I, Li S, Gu Y (2023) CALCIUM-DEPENDENT PROTEIN KINASE32 regulates cellulose biosynthesis through post-translational modification of cellulose synthase. BioRxiv doi: https://doi.org/10.1101/2023.02.01.526621
2022
Murshed M, Wei D, Gu Y, Wang J Modeling microtubule-cytoplasm interaction in plant cells. BioRxiv doi: https://doi.org/10.1101/2022.09.29.510138
2020
Zhu X, Tellier F, Gu Y, Li S (2020) Disruption of very-long-chain-fatty acid synthesis has an impact on the dynamics of cellulose synthase in Arabidopsis thaliana. Plants 9, 1599. Link
Makarem M, Nishiyama Y, Xin X, Durachko D, Gu Y, Cosgrove D, Seong K (2020) Distinguishing mesoscale polar order (Unidirectional vs. Bidirectional) of cellulose microfibrils in plant cell walls using sum frequency generation spectroscopy. J. Phys. Chem. 124, 37:8071-8081. Link
Xin X, Lei L, Zheng Y, Zhang T, Pingali SV, O’Neill H, Cosgrove DJ, Li S, Gu Y (2020) Cellulose synthase interactive1- and microtubules-dependent cell wall architecture is required for acid growth in Arabidopsis hypocotyls. J. Exp. Bot. 71(10) 2982-2994. Link
2019
Phyo P, Gu Y, Hong M (2019) Impact of acidic pH on plant cell wall polysaccharide structure and dynamics: insights into the mechanism of acid growth in plants from solid-state NMR. Cellulose 26(1):291-304. Link
2018
Zhu X, Li S, Pan S, Xin X, Gu Y (2018) CSI1, PATROL1 and exocyst complex cooperate in delivery of cellulose synthase complexes to the plasma membrane. Proc. Natl. Acad. Sci. USA 115:E3578-3587. Link
2016
Li S, Bashline L, Zheng Y, Xin X, Huang S, Kong Z, Kim SH, Cosgrove D, Gu Y (2016) Cellulose synthase complexes act in a concerted fashion to synthesize highly aggregated cellulose in secondary cell walls of plants. Proc. Natl. Acad. Sci. USA 113(40): 11348-11353 Link
Wang C, Hu T, Yan X, Meng T, Wang Y, Wang Q, Zhang X, Gu Y, Sánchez-Rodríguez C, Gadeyne A, Lin J, Persson S, Van Damme D, Li C, Bednarek SY, Pan J (2016) Differential regulation of Clathrin and its adaptor proteins during their membrane recruitment in Arabidopsis. Plant Physiol. 171(1): 215-229 Link
2015
Lei L, Singh A, Bashline L, Li S, Yingling YG, Gu Y (2015) The Arabidopsis cellulose synthase interactive 1 is required for a fast recycling of cellulose synthase complex to the plasma membrane. Plant Cell 27(10): 2926-2940 Link
Bashline L, Li S, Zhu X, Gu Y (2015) The TWD40-2 protein and the AP2 complex cooperate in the clathrin-mediated endocytosis of cellulose synthase to regulate cellulose biosynthesis. Proc. Natl. Acad. Sci. USA 112(41):12870-12875 Link
Wang S, Chen XA, Hu J, Jiang JK, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y (2015) ATF4 gene network mediate cellular response to the anticancer PAD4 inhibitor YW3-56. Mol. Cancer Ther. 14:877-888. PMID: 25612620 Link
2014
Brabham C, Lei L, Stork J, Barrett M, Gu Y, Debolt S (2014) Indaziflam herbicidal action: a potent cellulose biosynthesis inhibitor. Plant Physiol. 166(3):1177–1185 Link
Lei L, Zhang T, Strasser R, Lee CM, Gonneau M, Mach L, Vernhettes S, Kim SH, Cosgrove D, Li S, Gu Y (2014) The jiaoyao1 mutant is an allele of korrigan that affects the organization of both cellulose microfibrils and microtubules in Arabidopsis. Plant Cell 26(6):2601-2616 Link
Ye X, Lei L, Stork J, Brabham C, Strickland J, Ladak A, Gu Y, Debolt S (2014) Microbial natural product-based bioprospecting: identification of acetobixan as an inhibitor of plant cellulose biosynthesis. PLoS ONE DOI: 10.1371/journal.pone.0095245 Link
2013
Lei L, Li S, Du J, Gu Y (2013) Cellulose synthase interactive 3 regulates cellulose biosynthesis in both microtubule-dependent and microtubule-independent manner. Plant Cell 25(12):4912-4923 Link
Bashline L, Li S, Anderson CT, Lei L, Gu Y (2013) The endocytosis of cellulose synthase in Arabidopsis is dependent on u2, a clathrin mediated endocytosis adaptin. Plant Physiol. 163(1):150-160 Link
Chang F, Gu Y, Ma H, Yang Z (2013) AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth. Mol. Plant 6(4):1187-1201 Link
Li S, Lei L, Gu Y (2013) Functional analysis of complexes with mixed primary and secondary cellulose synthases. Plant Signal. Behav. 8(3): e23179 Link
2012
Carroll A, Mansoori N, Li S, Lei L, Vernhettes S, Visser R, Somerville C, Gu Y, Trindade, L (2012) Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants. Plant Physiol. 160(2):726-737 Link
Wang Y, Li P, Wang S, Hu J, Chen XA, Wu J, Fisher M, Oshaben K, Zhao N, Gu Y, Chen G, Wang Y. (2012) Anticancer PAD inhibitors regulate autophagy and the mammalian target of rapamycin complex 1 activity. J. Biochem. Chem. 287(31):25941-25953 Link
Lei L, Li S, Gu Y (2012) Cellulose synthase interactive protein 1 (CSI1) mediates the intimate relationship between cellulose microfibrils and cortical microtubules. Plant Signal. Behav. 7(7):714-718 Link
Li S, Lei L, Somerville CR, Gu Y (2012) Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc. Natl. Acad. Sci. USA 109(1):185-190 Link
2010
Gu Y, Kaplinsky N, Bringmann M, Cobb A, Carroll A, Sampathkumar A, Baskin TI, Persson S, Somerville C (2010) Identification of a cellulose synthase-associated protein required for cellulose biosynthesis. Proc. Natl. Acad. Sci. USA 107:12866-12871 Link
Publications before joining Penn State:
Gu Y, Deng ZP, Paredez AR, Debolt S, Wang ZY, Somerville C (2008) Prefoldin6 is required for normal microtubule dynamics and organization in Arabidopsis. Proc. Natl. Acad. Sci. USA 105:18064-18069 Link
Li S, Gu Y, Yan A, Lord E, Yang ZB (2008) RIP1 (ROP Interactive Partner 1)/ICR1 marks pollen germination sites and may act in the ROP1 pathway in the control of polarized pollen growth. Mol. Plant 6:1021-1035 Link
Jeon BW, Hwang JU, Hwang YK, Song WY, Fu Y, Gu Y, Bao F, Cho D, Kwak JM, Yang ZB, Lee Y (2008) The Arabidopsis small G protein ROP2 is activated by light in guard cells and inhibits light-induced stomatal opening. Plant Cell 20:75-87 Link
Gu Y, Li SD, Lord EM, Yang ZB (2006) Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Plant Cell 18:366-381 Link
Fu Y, Gu Y, Zheng ZL, Wasteneys G, Yang ZB (2005) Arabidopsis interdigitating cell growth requires two antagonistic pathways with opposing action on cell morphogenesis. Cell 120:687-700 Link
Gu Y, Fu Y, Dowd P, Li SD, Vernoud V, Gilroy S, Yang ZB (2005) A Rho-family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. J. Cell Biol. 169:127-138 Link
Hwang JU, Gu Y, Lee YJ, Yang ZB (2005) A Oscillatory ROP GTPase activation leads the oscillatory polarized growth of pollen tubes. Mol. Biol. Cell 16:5385-5399 Link
Park J, Gu Y, Lee Y, Yang ZB, Lee Y (2004) Phosphatidic acid induces leaf cell death in Arabidopsis by activating the Rho-related small G protein GTPase-mediated pathway of reactive oxygen species generation. Plant Physiol. 134:129-136 Link
Gu Y, Vernoud V, Fu Y, Yang ZB (2003) ROP GTPase regulation of pollen tube growth through the dynamics of tip-localized F-actin. J Exp. Bot. 54:93-101 Link
Wu G, Gu Y, Li SD, Yang ZB (2001) A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-containing proteins that act as Rop GTPase targets. Plant Cell 13:2841-2856 Link
2022
Gu Y, Rasmussen C (2022) Cell biology of primary cell wall synthesis in plants. Plant Cell 34:103-128. Link
2021
Allen H, Wei D, Gu Y, Li S (2021) A historical perspective on the regulation of cellulose biosynthesis. Carbohydrate Polymers 252 117022 Link
2015
Li S, Lei L, Yingling YG, Gu Y (2015) Microtubules and cellulose biosynthesis: the emergence of new players. Curr. Opin. Plant Biol. 28: 76-82 Link
2014
Lei L, Li S, Bashline L, Gu Y (2014) Dissecting the molecular mechanism underlying intimate relationship between cellulose microfibrils and cortical microtubules. Front. Plant Sci. doi: 10.3389/fpls.2014.00090 Link
Bashline L, Li S, Gu Y (2014) Trafficking of the cellulose synthase complex in higher plants. Ann. Bot. doi: 10.1093/aob/mcu040 Link
Bashline L, Lei L, Li S, Gu Y (2014) Cell wall, cytoskeleton, and cell expansion in higher plants. Mol. Plant 7(4): 586-600 Link
Li S, Bashline L, Lei L, Gu Y (2014) Cellulose biosynthesis and its regulation. The Arabidopsis Book 11:e0169. doi:10.1199/tab.0169 Link
2012
Li S, Gu Y (2012) Cellulose biosynthesis in higher plants and the role of the cytoskeleton. eLS doi: 10.1002/9780470015902.a0023745 Link
Baskin T, Gu Y (2012) Making parallel lines meet: Transferring information from microtubules to extra-cellular matrix. Cell Adhe. Migr. 6(5):1-5 Link
Lei L, Li S, Gu Y (2012) Cellulose synthase complexes: composition and regulation. Front. Plant Physiol. 3:75 doi: 10.3389/fpls.2012.00075 Link
2011
Bashline L, Du J, Gu Y (2011) The trafficking and behavior of cellulose synthase and a glimpse of potential cellulose synthesis regulators. Front. Biol. 6(5):377-383 Link
2010
Gu Y, Somerville C (2010) Cellulose synthase interacting protein: a new factor in cellulose synthesis. Plant Signal. Behav. 5(12):1571-1574 Link
Publications before joining Penn State:
Gu Y, Wang ZH, Yang ZB (2004) ROP/RAC GTPase: an old new master regulator for plant signaling. Curr. Opin. Plant Biol. 7:527-536 Link
Zhu X, Xin X, Gu Y (2019) Cellulose and hemicellulose synthesis and their regulation in plant cells. Book chapter, Extracellular sugar-based biopolymer matrices. DOI 10.1007/978-3-030-12919-4, Ephraim Cohen and Hans Merzendorfer, ed. Springer Nature Switzerland AG.
Bashline L, Gu Y (2015) Using the Split-Ubiquitin yeast two-hybrid systems to test protein-protein interactions of transmembrane proteins. In: Plant Cell Expansion: Methods and Protocols. Method. Mol. Biol. vol. 1242, DOI 10.1007/978-1-4939-1902-4_13, Springer Science, New York. Link
Penn State News highlighted the research from Gu Lab: “Newly identified protein regulates the creation of cellulose in plant cells”. Link
Penn State News highlighted the research from Gu Lab: “Herringbone pattern in plant cell walls critical to cell growth.” Link
Xiaoyu Zhu received the 2018 Robert T. Simpson Graduate Student Award for Innovative Research. Link
Penn State News highlighted the research from Gu Lab: “New insights into how cellulose is built could indicate how to break it apart for biofuels.” Link
A Penn State Research article highlights the research of Gu LAB researchers at Penn State: “The key to efficient biofuels may lie in learning how plants build their cell wall.” Full story (page 21-24): Link
Logan Bashline was invited to make a video of his current work to be used as part of a video series that showcases the accomplishments of successful Waynesburg alumni.